The Browns went 3 and out on their first possession, and then Hoyer got hurt on their second possession.
Hoyer scrambled on 2nd and 9 from the Cleveland 36 and picked up a first down on his run. But as Bills linebacker Kiko Alonso closed in, he attempted to slide. However, Alonso tackled him as he was sliding, which caused his leg to twist under his body in a bad way.
Brandon Weeden came in for Hoyer, who walked to the locker room. Hoyer, a former Michigan State and New England Patriots quarterback, was 2-0 on the season and had given Browns fans a reason to be optimistic. Their prospects of winning are much worse with Weeden.
Below is another angle of the slide: