• Skip to main content
  • Skip to header right navigation
  • Skip to site footer
Larry Brown Sports

Larry Brown Sports

Brown Bag it, Baby

  • Home
  • Blog View
  • NFL
  • NCAAF
  • NBA
  • MLB
  • Media
  • Headlines
  • Podcast
FootballIsaac GuerendoSan Francisco 49ers

49ers lose another key offensive player to injury

December 19, 2024 by Steve DelVecchio • Comments
FacebookTweetLinkedInRedditThreadsWhatsAppEmail
The San Francisco 49ers logo at midfield
Nov 12, 2018; Santa Clara, CA, USA; A general overall view of the San Francisco 49ers logo at midfield at Levi's Stadium prior to the game against the New York Giants. Mandatory Credit: Kirby Lee-USA TODAY Sports

The San Francisco 49ers have been ravaged by injuries this season, and it sounds like they have lost yet another running back for at least a week.

Isaac Guerendo is dealing with a hamstring injury that will likely sideline him for Sunday’s game against the Miami Dolphins, according to ESPN’s Adam Schefter.

After losing RBs Christian McCaffrey, Jordan Mason and Elijah Mitchell to season-ending injuries, it now looks as if the 49ers will be without RB Isaac Guerendo for Sunday’s game vs. Miami. Guerendo is dealing with a hamstring injury and is unlikely to play, per source. pic.twitter.com/PyqyBCqPoT

— Adam Schefter (@AdamSchefter) December 19, 2024

Guerendo has done an admirable job as the next, next, (next?) man up for the 49ers. The rookie has 381 rushing yards and has averaged 5.1 yards per carry. He handled the bulk of the work in San Francisco’s backfield the last two weeks after both Christian McCaffrey and Jordan Mason were put on injured reserve. McCaffrey and Mason joined Elijah Mitchell, who had surgery after suffering a hamstring injury during the preseason.

In addition to all of their running backs, the Niners also lost star wide receiver Brandon Aiyuk to a torn ACL in Week 7. The injuries are a big reason why they are 6-8 and all but eliminated from playoff contention.

If Guerendo does miss Sunday’s game, fourth-year back Patrick Taylor Jr. would be in line to start.

  • i want more great stories!

Sign up today for free and get the best sports content sent to your inbox.

You can unsubscribe anytime. For more details, review our Privacy Policy.

.

Follow Us

Get instantly notified of the most viral news stories via Google!

  • Trending stories

Aaron Rodgers delivers a pass

Aaron Rodgers’ 2026 plans may already be clear

2 days ago
Bryce Harper holding a helmet

Bryce Harper makes brutally honest comment about Phillies’ manager change

4 days ago
Kurt Warner working an NFL game

Kurt Warner’s son lands NFL rookie camp invitation

3 days ago
Taylor Heinicke on the practice field

Former cult hero NFL quarterback announces his retirement

2 days ago
Giannis Antetokounmpo drives to the basket.

Report: Giannis Antetokounmpo’s brothers are turning off 1 interested team

4 days ago

Sidebar


  • don’t miss these

Bears helmet on the field

Bears penalty data reveals questionable officiating trend

2 hours ago209
Tyreek Hill runs with the ball

Tyreek Hill settles lawsuit with influencer: ‘Going to Disney World’

4 hours ago100
Joel Embiid looks ahead

Joel Embiid has salty comments after going down 0-3 to Knicks

10 hours ago60
Dianna Russini on a red carpet

New report addresses whether Dianna Russini named her son after Mike Vrabel

19 hours ago921
Breece Hall talks with the media

Breece Hall offers touching comment after receiving big contract extension

19 hours ago279
Aaron Rodgers in a Steelers hoodie

Steelers GM addresses the latest Aaron Rodgers rumor

19 hours ago342
  • popular stories

Angel Reese watching an NBA game

Pistons fans troll Angel Reese during Game 7 win over Magic

Jarred Vanderbilt hitting his finger

Lakers’ Jarred Vanderbilt suffers gruesome finger injury in Game 1 vs. Thunder

The Denver Broncos logo

Broncos emerge as possible landing spot for QB known for a notorious game

Mike Vrabel at a press conference

Report: Mike Vrabel, Dianna Russini rented a boat together while she was pregnant

Warriors coach Steve Kerr in a blue warmup jacket

Steve Kerr’s talks with Warriors leading to 1 increasingly likely outcome

Fernando Mendoza wearing a Raiders cap

Fernando Mendoza reveals why he is skipping Indiana’s White House visit

Get the App

© 2026 · LB Sports Media Group Inc · Powered by Springwire.ai

  • X
  • Facebook
  • YouTube
  • Instagram
  • RSS Feed
  • About Larry Brown Sports
  • Contact
  • Editorial Process
  • Staff Writers
  • Privacy Policy
Dedicated to the memory of Nevil Vega
Team/Player Stats